International Institute of Rare Sugar Research and Education

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Division of Application Development

Physical Sciences

 This field clarifies the physicochemical properties of crystallized rare sugars by various molecular structure analyses and physicochemical analyses, and promotes fundamental researches for development of rare sugar uses in the industrial context.

Tomohiko Ishii, Genta Sakane, Akihide Yoshihara, Kazuhiro Fukada and Tatsuya Senoo. 2015. Crystal structure of β-D,L-psicose.

Acta Cryst. E71: o289–o290

Researchers

Fukada, Kazuhiro
Professor
Nakanishi, Shunsuke
Dean of Engineering & Professor
Ishii, Tomohiko
Professor
Takao, Hidekuni
Director of Micro-Nano Structure Device Integrated Research Center & Professor
Kakegawa, Hisao
Professor
Okazaki, Shinichiro
Associate Professor
Terao, Kyohei
Associate Professor
Isoda, Kyosuke
Lecturer

Molecular Tool Development

 This field promotes a fundamental research on an innovation of the new face in life sciences using rare sugars as a molecular tool rather than simple energy sources as intermediate metabolites for energy transmission.

Kagawa University is the only research organization in the world, which can supply all kinds of rare sugars for various types of research and development.

Researchers

Kakehi, Yoshiyuki
Director & Board of Trustee
Kadowaki, Norimitsu
Professor
Minamino, Tetsuo
Professor
Hoshino, Katsuaki
Professor
Sugimoto, Mikio
Associate Professor
Taoka, Rikiya
Assistant Professor

Clinical Trial

 This field carries all responsibilities of clinical trials for the application of the rare sugars. Accumulation of repeated evidences will lead to make use of rare sugars in the treatment such as diabetes in the future.

Rare sugars and a part of the results of the clinical trials were shown in NHK nationwide broadcasting program "Good Morning Japan" in June, 2016.

Researchers

Murao, Koji
Professor
Imachi, Hitomi
Associate Professor
Yoshimoto, Takuo
Assistant Professor
Kikuchi, Fumi
Assistant Professor
Fukunaga, Kensaku
Assistant Professor

Microbial Sciences

 This field promotes a fundamental research on rare sugar producing enzymes using microbes such as purifications, enzymatic reactions, structural analyses for chemical characterizations and application developments.

Kenji Morimoto1, Akihide Yoshihara, Toshio Furumoto, Goro Takata 2015. Production and application of a rare disaccharide using sucrose phosphorylase from Leuconostoc mesenteroides.

J. Biosci. Bioeng.119: 652–656.

Researchers

Asada, Yasuhiko
Professor
Sakuraba, Haruhiko
Professor
Takada, Goro
Associate Professor
Morimoto, Kenji
Associate Professor

Animal Sciences

 This field promotes a fundamental research on various mode of actions of rare sugars for animals and animal cells for the development of applications using the identified mode of actions.

KMasashi Sato, Nobutoshi Yokoi, Hiroyuki Kurose, and Toru Yamasaki 2009. D-Ribose Competitively Reverses Inhibition by D-Psicose of Larval Growth in Caenorhabditis elegans.

J. Biosci. Bioeng.119: 652–656.

Researchers

Sato, Masashi
Professor
Kawanami, Yasuhiro
Professor
Miyake, Minoru
Professor
Hoshikawa, Hiroshi
Professor
Arai, Meiji
Associate Professor
Yamaguchi, Fuminori
Associate Professor
Tsukamoto, Ikuko
Professor
Yanagida, Ryo
Associate professor
Sugiyama, Yasunori
Assistant professor
Kawasaki, Kiyonori
Assistant professor
Ogawa, Takaaki
Assistant Professor
Kamitori, Kazuyo
Assistant Professor

Plant Sciences

 This field promotes a fundamental research on rare sugar actions to plants and plant cells for development of applications as agriculture materials. In addition, an elucidation of various characteristic of Itea plant producing rare sugars is also progressing.

Akihito Kano, Takeshi Fukumoto, Kouhei Ohtani, Akihide Yoshihara, Toshiaki Ohara, Shigeyuki Tajima, Ken Izumori, Keiji Tanaka, Takeo Ohkouchi, Yutaka Ishida, Yoko Nishizawa, Kazuya Ichimura, Yasuomi Tada, Kenji Gomi and Kazuya Akimitsu 2013. The rare sugar D-allose acts as a triggering molecule of rice defence via ROS generation.

J. Exp. Bot. 64: 4939-4951.

Researchers

Akimitsu, Kazuya
Assistant Director & Professor
Kataoka, Ikuo
Dean of Agriculture & Professor
Fukai, Seiichi
Professor
Takamura, Takejiro
Professor
Nomura, Mika
Professor
Ichimura, Kazuya
Associate Professor
Gomi, Kenji
Associate Professor

Food Sciences

 This field analyzes rare sugar action properties and food properties such as antioxidative property or viscoelasticity of the thermally processed rare sugar added food to advance the fundamental researches to be connected for food development with an advantage of rare sugar functions.

Siwaporn O'Charoen, Shigeru Hayakawa and Masahiro Ogawa 2015. Food properties of egg white protein modified by rare ketohexoses through Maillard reaction.

Int. J. Food Sci. Technol. 50: 194–202.

Researchers

Ogawa, Masahiro
Professor
Matsuo, Tatsuhiro
Professor
Gotani, Shoichi
Director of the Center of Social Collaboration and Intellectual Property & Professor
Kawamura, Osamu
Professor
Tamura, Hirotoshi
Professor
Yoshii, Hidehumi
Professor
Yonekura, Lina
Assistant Professor

Teaching Material Development

 This field uses Itea plant as a unique educational material for Kagawa region, which is the only plant known at present to contain rare sugars, and presents itself as a teaching material development study by cooperation with Kagawa Itea Research Meeting or the Kagawa CST Program.

Rare sugars and Itea plant were shown in NHK nationwide broadcasting program "Science Zero" in May, 2013.

Researchers

Kitabayashi, Masahiro
Professor
Yamashita, Naoko
Professor
Miyake, Takashi
Associate Professor
Komori, Hirofumi
Associate Professor
Shinohara, Wataru
Associate Professor
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